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Lab Technician Previous Year Paper Pdf,Paramedical lab technician question papers,

 1. Which of the following is known as Guardian of genome?

(1) p53

(2) PTEN

(3) ATM

(4) MDM 2

ANSWER- 1

2. Cells most sensitive to hypoxia are

(1) Myocardial cells

(2) Neurons

(3) Hepatocytes

(4) Renal tubular epithelial cells

ANSWER- 2

 

3.Fibrosis is due to

(1) TGF-β

(2) IL-7

(3) IL-10

(4) VEGF

ANSWER- 1

 

4.Leiden factor is

(1) Factor VI

(2) Factor IV

(3) Factor VIII

(4) Factor V

ANSWER- 4

 

5.Macroglossia is seen in

(1) Amyloidosis

(2) Folic acid deficiency

(3) Iron deficiency

(4) Motor neurone disease

ANSWER- 1

6. Lines of Zahn occur in

(1) Coralline thrombus

(2) Embolus

(3) Infarct

(4) Post Mortem Clot

 ANSWER- 1

 

7. Basement membrane consist of

(1) Type I collagen

(2) Type II collagen

(3) Type III collagen

(4) Type IV collagen

ANSWER- 4

 

8. Tubercle bacilli in caseous lesions are best demonstrated in

(1) Caseous centre

(2) Margin of necrosis with viable tissue

(3) Epithelioid cells

(4) Langhans' giant cells

ANSWER- 2

 

9. Transudate differs from exudate in having the following, except:

(1) No inflammatory cells

(2) Low protein content

(3) Low specific gravity

(4) Low glucose content

ANSWER- 4

 

10. Granuloma is formed by

(1) Neutrophil

(2) Cytotoxic cell

(3) Helper T cell

(4) NK Cells

ANSWER- 3

 

11. HIV is which type of virus?

(1) Pox virus

(2) Herpes virus

(3) Picorna virus

(4) Retro virus

ANSWER- 4

12. The causative organisms of plague are

(1) Yersinia pestis

(2) Haemophilus ducreyi

(3) Bordetella pertusis

(4) Pseudomonas aeruginosa

ANSWER- 1

 

13. Malignant cerebral Malaria caused by

(1) P. vivax

(2) P. falciparum

(3) P. ovale

(4) P. malariae

ANSWER- 2

 

14. Elevation of carcino embryonic antigen (CEA) level is seen in

(1) Liver Cell Cancer

(2) Ovarian Cancer

(3) Breast Cancer

(4) Carcinoma of Colon

ANSWER- 4

15. In Good pasture disease, the antigen is

(1) Basement membrane collagen IV

(2) Bacterial products

(3) Cationic products

(4) DNA

ANSWER- 1

 

16. Most common paraneoplastic syndrome associated with squamous cell carcinoma of Lung :

(1) Hypercalcemia

(2) Cushing syndrome

(3) Carcinoid syndrome

(4) Hypoglycemia

ANSWER- 1

 

17. Most common tumour of Heart is

(1) Leiomyosarcoma

(2) Myxoma

(3) Fibroma

(4) Rhabdomyosarcoma

ANSWER- 2

 

18. Popcorn cell seen in which type of Hodgkin's Lymphoma ?

(1) Nodular Sclerosis type

(2) Mixed Cellularity type

(3) Lymphocyte predominance type

(4) Lymphocyte depletion type

ANSWER-3

 

19. Chronic gastritis is caused by all, except:

(1) Alcohol

(2) Overuse of salicylates

(3) Helicobacter pylori

(4) Pernicious anaemia

ANSWER- 2

 

20. Mallory bodies seen in

(1) Primary biliary Cirrhosis

(2) Hepatitis C infection

(3) Post necrotic cirrhosis

(4) Amebic liver abscess

ANSWER- 1

 

21. Kimmel stiel-Wilson characteristic of:

(1) Diabetic nephropathy

(2) HIV nephropathy

(3) Malignant Hypertension

(4) Renal Cell Carcinoma

ANSWER- 1

 

22. In 50-80 percent cases of acute appendicitis, the inflammatory lesion initiated by

(1) Bacterial infection

(2) Luminal obstruction

(3) Viral infection

(4) Ischemia

ANSWER- 2

 

23. Malakoplakia of Urinary bladder is a form of

(1) Dysplasia

(2) Metaplasia

(3) Papillary hyperplasia

(4) Chronic inflammation

ANSWER- 4

 

24. Heubner arteritis is

(1) Endarteritis Obliterans

(2) Cerebral Syphilitic arteritis

(3) Hypersensitivity vasculitis

(4) Giant cell arteritis

ANSWER- 2

 

25. Curschmann spirals are seen in

(1) Chronic Bronchitis

(2) Bronchiectasis

(3) Bronchial Asthma

(4) Wegner's Granulomatosi

ANSWER- 3

 

26. Type of Emphysema associated most often with α-1 antitrypsin deficiency is

(1) Panacinar Emphysema

(2) Distal Emphysema

(3) Centrilobular Emphysema

(4) Irregular Emphysema

ANSWER- 1

 

27. The most common Lung cancer in women and non-smokers is

(1) Small Cell Carcinoma

(2) Squamous Cell Carcinoma

(3) Adenocarcinor

(4) Large Cell Carcinoma

ANSWER- 3

 

28. Lichen Planus is characterized by following, except :

(1) Lymphocytic infiltrate at damoepidermal junction

(2) Resolution of Basal layer

(3) Presence of elongated and broad rete ridges

(4) Presence of Civatte bodies

ANSWER- 3

 

29. Patients of AIDS have the following  type of oral leukoplakia:

(1) Speckled

(2) Hairy

(3) Nodular

(4) Wrinkled

ANSWER- 2

 

30. Bilaterally Symmetrical Contracted Kidney is seen in

(1) Nephrosclerosis

(2) Chronic Pyelonephritis

(3) Chronic Glomerulonephritis

(4) End stage renal disease

ANSWER- 3

 

31. Cowdry body seen in

(1) Astrocytes

(2) Neuron

(3) Oligodendroglia

(4) Microglia

ANSWER- 2

 

32. Seminoma is a

(1) Benign tumour

(2) Borderline tumour

(3) Malignant tumour

(4) Locally aggressive tumour

ANSWER- 3

 

33. Caplan's syndrome may develop in the following types of pneumoconiosis, except:

(1) Berylliosis

(2) Asbestosis

(3) Coal-Worker's pneumoconiosis

(4) Silicosis

ANSWER- 1

 

34. Crohn's disease is characterised by the following histopathologic features, except

(1) Stricture formation in chronic cases

(2) Widening of submucosa due to oedema

(3) Superficial mucosal ulceration

(4) Non-caseating sarcoid like granulomas

ANSWER- 3

 

34. Crohn's disease is characterised by the following histopathologic features, except:

(1) Stricture formation in chronic cases

(2) Widening of submucosa due to oedema

(3) Superficial mucosal ulceration

(4) Non-caseating sarcoid like granulomas

ANSWER- 3

 

35. Marker of level of progressive liver damage in case of hepatitis B is

(1) IgG anti HBs

(2) Anti HCV antibodies

(3) HBV DNA

(4) HBc Antigen

ANSWER- 3

 

36. Psammoma bodies are found in

(1) Follicular Carcinoma Thyroid

(2) Adenocarcinoma Breast

(3) Adenocarcinoma Stomach

(4) Serous ovarian tumour

ANSWER- 4

 

37. Paget's Disease has a risk for

(1) Osteoma

(2) Osteosarcoma

(3) Fibrosarcoma

(4) Fibroadenoma

ANSWER- 2

 

38. Osteoclasts are stimulated by

(1) Calcitonin

(2) Parathyroid hormone (PTH)

(3) Estrogen

(4) Thyroxin

ANSWER- 2

 

39. The following types of carcinoma of the Breast is characterized by Single file pattern of tumour cells:

(1) Infiltrating duct carcinoma

(2) Invasive lobular carcinoma

(3) Medullary Carcinoma

(4) Tubular Carcinoma

ANSWER- 2

 

40. BRCA 2 not associated with

(1) Breast cancer

(2) Pancreatic cancer

(3) Ovarian cancer

(4) Vulval cancer

ANSWER- 4

 

41. Which of the following is post inflammatory pseudotumour of Ear?

(1) Otosclerosis

(2) Cholesteatoma

(3) Chondrodermatitis nodularis

(4) Paraganglioma

ANSWER- 2

 

42. Molluscum Contagiosum caused by

(1) Human Papilloma Virus

(2) Pox Virus

(3) Herpes Simplex Virus

(4) Ebstein Bar Virus

ANSWER- 2

 

43. Conn Syndrome is

(1) Chronic hypercortisolism

(2) Secondary hyperaldosteronism

(3) Primary hyperaldosteronism

(4) Adrenogenital Syndrome

ANSWER- 3

 

44. Strap Cells in histopathology are seen in

(1) Rhabdomyosarcoma

(2) Rhabdomyoma

(3) Histiocytoma

(4) Leiomyosarcoma

ANSWER- 1

 

45. Sjogren's syndrome produces the following pathological change in the Eуе

(1) Uveitis

(2) Glaucoma

(3) Keratoconjunctivitis

(4) Phthisis bulbi

ANSWER- 3

 

46. The following tumour is characterized by biphasic pattern of growth

(1) Osteosarcoma

(2) Osteochondroma

(3) Malignant fibrous histiocytoma

(4) Synovial sarcoma

ANSWER- 4

 

47. In rheumatic fever fibrinoid necrosis occurs in

(1) Collagen

(2) Myocardium

(3) Pericardium

(4) Endocardium

ANSWER- 1

 

48. Duodenal ulcers are found most commonly at

(1) First part, anterior surface

(2) First part, posterior surface

(3) Second part, anterior surface

(4) Second part, posterior surface

ANSWER- 1

 

49. Barrett's oesophagus predispose to development of

(1) Reflux oesophagitis

(2) Oesophageal varices

(3) Squamous cell carcinoma

(4) Adenocarcinoma

ANSWER- 4

 

50.The following type of renal calculi are radiolucent

(1) Calcium phosphate

(2) Uric acid

(3) Magnesium ammonium phosphate

(4) Cystine

ANSWER- 2

51. Lymphatic metastasis of Prostatic  carcinoma occur initially to

(1) Obturator lymph node

(2) Perivesical lymph node

(3) Iliac lymph node

(4) Presacral lymph node

ANSWER- 1

 

52. Krukenberg tumour is bilateral metastatic tumour from the following primary site, except :

(1) Colon

(2) Endometrium

(3) Ovary

(4) Stomach

ANSWER- 2

 

53. Which is the most frequently altered oncogene in Pancreatic cancer?

(1) K-ras

(2) RB1 (139)

(3) MKK4 (17p)

(4) MYB (69)

ANSWER- 1

 

54. Herring bone pattern seen in

(1) Fibrosarcoma

(2) Leiomyoma

(3) Osteoma

(4) Osteosarcoma

ANSWER- 1

 

55. Bullous lesion of the skin is

(1) Lichen Planus

(2) Seborrhoeic dermatitis

(3) Pemphigus Vulgaris

(4) Psoriasis

ANSWER- 3

 

56. Antoni A and Antoni B growth pattern seen in

(1) Schwannoma

(2) Neurofibroma

(3) Meningioma

(4) Ganglioma

ANSWER- 1

 

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